despite (或 in despite of)

(archaic)in spite of

(古)不管，尽管，任凭

despite oneself

used to indicate that one did not intend or expect to do the thing mentioned

不由自主地；身不由己地

despite herself Fran felt a ripple of appreciation for his beauty.

弗兰不由自主地感受到了他的勃勃英姿。